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Applying SF‑6D to measure health state utilities among the middle and old aged patients with hypertension in China
    发布日期:2020-12-23       阅读次数:
Abstract

Purpose: Hypertension is a growing public health problem in China; however, little is known about health-related quality of life (HRQoL) especially health state utility (HSU) of patients with hypertension in rural China. This study aimed to examine the HSU as measured by SF-6D and to investigate its associated factors among middle and old aged patients with hypertension in rural China.

Methods: Data were collected from twelve villages in Shandong Province in 2016. SF-36 was administrated to measure HRQoL of middle and old aged patients with hypertension and was got to the SF-6D values using Hong Kong’s tariff. Descriptive analyses, such as demographic characteristics, socio-economic status, and utility, were stratified by hypertension classification. Multiple linear regression models were applied to assess the associated factors of HSU.

Results: A total of 933 (response rate:86.4%) middle and old aged patients (69.1±8.2 years) with hypertension participated in the study. 39.4% of participants were male; 44.2% had stage I hypertension; 26.4% had stage II and above. The mean score of SF-6D utility score was 0.743 (SD: 0.14, range: 0.32–1.00, median: 0.756, Interquartile range:0.634–0.859). Being female (β=0.046), having two or more comorbidities (2 vs. 1 β=0.066;>3 vs. 1 β=0.098) and the health expenditure higher than 2000 RMB (20003999 vs.< 2000 β=0.042; 4000–5999 vs. <2000 β=0.046;> 6000 vs. < 2000 β=0.071) were significantly associated with lower SF-6D overall score; while being farmer (β=0.032), having high household income (10,00014,999 vs. < 5000 β=0.045; > 15,000 vs. < 5000 β=0.064) and having stage I and above hypertension (stage I vs. Normotensive β=0.047; stage II vs. Normotensive β=0.079; stage III vs. Normotensive β=0.095) were significantly associated with higher SF-6D overall score.

Conclusion: SF-6D was capable to measure quality of life middle and old aged patients with hypertension in China. And multiple factors were demonstrated to be significantly associated with quality of life.

Keywords: Health utility, Hypertension, Preference-based measurement, Quality of life, SF-6D


作者:Xiaohan LiuGuannan BaiHui Li and Shunping Li

出处:《Health and Quality of Life Outcomes202012